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The therapeutic potential of the glucagon-like peptide-1 (GLP-1) and the glucose-dependent insulinotropic polypeptide/GLP-1 (GIP/GLP-1) receptor agonists extends beyond the regulation of glycemia, including glucometabolic, cardiovascular, and renal effects, rendering them viable candidates, due to their mechanisms of action, for the possible treatment of respiratory disorders
It works on a different receptor system the amylin receptor meaning it addresses appetite and weight through a biological pathway that GLP-1 medications do not directly target
Senolytic Peptide FOXO4-DRI Selectively Removes Senescent Cells From in vitro Expanded Human Chondrocytes. Frontiers in bioengineering and biotechnology vol
The receptor work is genuinely old: the angiotensin IV target was identified as the enzyme IRAP back in 2001
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